Impact papers on aging in 2009 - eScholarship

The editorial board of Aging reviews research papers published in 2009,which they believe have or will have a significant impact on aging research. Among many others, the topics include genes that accelerate aging or incontrast promote longevity in model organisms, DNA damage responsesand telomeres, molecular mechanisms of life span extension by calorierestriction and pharmacologic interventions into aging. The emergingmessage in 2009 is that aging is not random but determined by agenetically-regulated longevity network and can be decelerated bothgenetically and pharmacologically. © Blagosklonny et al.