IL-37 requires the receptors IL-18Ra and IL-1R8 (SIGIRR) to carry out its multi-faceted anti-inflammatory program on innate signal transduction

Chistopher Nold; Charles G. Lo; Ina Rudloff; Kirstin Elgass; S. Li; Michael P. Gantier; A. Lotz-Hayla; Søren W. Gersting; S. Cho; Juanfeng Lao; Andrew M. Ellisdon; Björn Rotter; Tania Azam; Niamh E. Mangan; F. Rosello; James C. Whisstock; Philip Bufler; Cecília Garlanda; Alberto Mantovani; C A Dinarello; Marcel F. Nold

Related publications

Article2015

IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction

Claudia A. Nold‐Petry, Camden Lo, Ina Rudloff, Kirstin Elgass, Suzhao Li, Michael P. Gantier, Amelie S. Lotz‐Havla, Søren W. Gersting, Steven Cho, Jason Chun Lao, Andrew M. Ellisdon, Björn Rotter, Tania Azam, Niamh E. Mangan, Fernando J. Rossello, James C. Whisstock, Philip Bufler, Cecília Garlanda, Alberto Mantovani, Charles A. Dinarello, Marcel F. Nold

Article2011

CS05-3. Interleukin 37 exerts its anti-inflammatory functions by associating with IL-18Rα and SIGIRR

Marcel F. Nold, Claudia A. Nold‐Petry, Jarod A. Zepp, Camden Lo, Cecília Garlanda, Alberto Mantovani, Philip Bufler, Charles A. Dinarello

Article2013

Interleukin 37 employs the IL-1 family orphan receptor SIGIRR and the alpha chain of the IL-18 receptor to inhibit innate immunity (P6293)

Claudia A. Nold‐Petry, Marcel F. Nold, Ina Rudloff, Camden Lo, Niamh E. Mangan, Bjoern Rotter, Jarod A. Zepp, Tania Azam, Suzhao Li, Ashley Mansell, Philip Bufler, Cecília Garlanda, Alberto Mantovani, Charles A. Dinarello

Article2015

Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8

Suzhao Li, C. Preston Neff, Kristina Barber, Jaewoo Hong, Yuchun Luo, Tania Azam, Brent E. Palmer, Mayumi Fujita, Cecília Garlanda, Alberto Mantovani, Soohyun Kim, Charles A. Dinarello

Chapter in a book2006

Tuning of inflammatory cytokines and toll-like receptors by TIR8/SIGIRR, a member of the IL-1 receptor family with unique structure and regulation

Cecília Garlanda, Michela Mosca, Alessia Cotena, Virginia Maina, Federica Moalli, Federica Riva, Alberto Mantovani