Identifying the Distinct Cognitive Phenotypes in Multiple Sclerosis

Ermelinda De Meo; Emilio Portaccio; Antonio Giorgio; Luís Ruano; Benedetta Goretti; Claudia Niccolai; Francesco Patti; Clara Grazia Chisari; Paolo Gallo; Paola Grossi; Angelo Ghezzi; Marco Roscio; Flavia Mattioli; Chiara Stampatori; Marta Simone; Rosa Gemma Viterbo; Raffaello Bonacchi; Maria A. Rocca; Nicola De Stefano; Massimo Filippi; Maria Pia Amato

doi:10.1001/jamaneurol.2020.4920

Abstract

1 min read

This study found that by defining homogeneous and clinically meaningful phenotypes, the limitations of the traditional dichotomous classification in MS can be overcome. These phenotypes can represent a more meaningful measure of the cognitive status of patients with MS and can help define clinical disability, support clinicians in treatment choices, and tailor cognitive rehabilitation strategies.

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