Identification of novel diarylpyrimidine derivatives as potent HIV-1 non-nucleoside reverse transcriptase inhibitors against wild-type and K103N mutant viruses

Xiangyi Jiang; Waleed A. Zalloum; Zhen Gao; Jiaojiao Dai; Xiangkai Ji; Minghui Xie; Guanyu Dong; De Clercq Erik; Boshi Huang; Christophe Pannecouque; Peng Zhan; Xinyong Liu

doi:10.1016/j.ejmech.2024.116941

Back

Identification of novel diarylpyrimidine derivatives as potent HIV-1 non-nucleoside reverse transcriptase inhibitors against wild-type and K103N mutant viruses

Article 2024 en

Related publications

Article2007

Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains

Maria Letizia Barreca, Angela Rao, Laura De Luca, Nunzio Iraci, Anna‐Maria Monforte, Giovanni Maga, De Clercq Erik, Christophe Pannecouque, Jan Balzarini, Alba Chimirri

Article2007

Discovery of Novel Benzimidazolones as Potent Non‐Nucleoside Reverse Transcriptase Inhibitors Active Against Wild‐Type and Mutant HIV‐1 Strains.

Maria Letizia Barreca, Angela Rao, Laura De Luca, Nunzio Iraci, Anna‐Maria Monforte, Giovanni Maga, De Clercq Erik, Christophe Pannecouque, Jan Balzarini, Alba Chimirri

Article2022

Identification of Boronate-Containing Diarylpyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

Da Feng, Hao Lin, Liyang Jiang, Zhao Wang, Yanying Sun, Zhongxia Zhou, De Clercq Erik, Christophe Pannecouque, Dongwei Kang, Peng Zhan, Xinyong Liu

Article2013

Novel piperidinylamino-diarylpyrimidine derivatives with dual structural conformations as potent HIV-1 non-nucleoside reverse transcriptase inhibitors

Xuwang Chen, Xin Liu, Qing Meng, Ding Wang, Huiqing Liu, De Clercq Erik, Christophe Pannecouque, Jan Balzarini, Xinyong Liu

Article2025

Structure-Based Drug Design Yields Diarylpyrimidine Derivatives as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

Zhenzhen Zhou, Jie Guo, Xin Li, Jinyuan Wu, De Clercq Erik, Christophe Pannecouque, Peng Zhan, Dongwei Kang, Xinyong Liu

Identification of novel diarylpyrimidine derivatives as potent HIV-1 non-nucleoside reverse transcriptase inhibitors against wild-type and K103N mutant viruses

Discussion(0)

Related publications

Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains

Discovery of Novel Benzimidazolones as Potent Non‐Nucleoside Reverse Transcriptase Inhibitors Active Against Wild‐Type and Mutant HIV‐1 Strains.

Identification of Boronate-Containing Diarylpyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

Novel piperidinylamino-diarylpyrimidine derivatives with dual structural conformations as potent HIV-1 non-nucleoside reverse transcriptase inhibitors

Structure-Based Drug Design Yields Diarylpyrimidine Derivatives as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors