We report the first two documented cases of neonatal zygomycosis caused by Absidia corymbifera. A premature infant developed disseminated disease from a cutaneous site with pulmonary, gastrointestinal, and cerebral involvement. The infant died despite amphotericin B therapy and surgical debridement. The second case occurred in a full-term infant with congenital heart disease and fungal pneumonitis. Zygomycosis was not suspected because of underlying cardiac disease and a complicated postoperative course, and this infant also died. Absidia joins a growing list of opportunistic fungal pathogens of the compromised neonate.
Makoto Saito, Mary Ellen Gilder, Verena I. Carrara, Laypaw Archusuksan, Hsa Eh, Naw Eh, Ma Ner, Aye Kyi Win, Laaongsri Niwetphongprai, Urairat Koesukwiwat, Joel Tärning, Sir Nicholas White, François Nosten, Rose McGready
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