Hypoxia Controls the Glycome Signature and Galectin-8–Ligand Axis to Promote Protumorigenic Properties of Metastatic Melanoma

Asmi Chakraborty; Mariana Perez; Jordan D. Carroll; Aristotelis Antonopoulos; Anne Dell; Liettel Ortega; Norhan Mohammed; Michael Wells; Caleb Staudinger; Anthony J. Griswold; Kevin Brown Chandler; Cristina Velazquez Marrero; Ramon E. Jimenez; Yoshihiko Tani; James S. Wilmott; John F. Thompson; Wei Wang; Robert Sackstein; Richard A Scolyer; Gëorge F. Murphy; Stuart M. Haslam; Charles J. Dimitroff

doi:10.1016/j.jid.2022.07.033

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Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma

Ke Hu, Savalan Babapoor-Farrokhran, Murilo Wendeborn Rodrigues, Monika Deshpande, Brooks Puchner, Fabiana Kashiwabuchi, Syed Junaid Hassan, Laura Asnaghi, James T. Handa, Shannath L. Merbs, Charles G. Eberhart, Gregg L. Friedman, Silvia Montaner, Akrit Sodhi

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Correction: Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma

Ke Hu, Savalan Babapoor-Farrokhran, Murilo Wendeborn Rodrigues, Monika Deshpande, Brooks Puchner, Fabiana Kashiwabuchi, Syed Junaid Hassan, Laura Asnaghi, James T. Handa, Shannath L. Merbs, Charles G. Eberhart, Gregg L. Friedman, Silvia Montaner, Akrit Sodhi

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Abstract B8: Galectin-1 expressed in human melanoma is bound to cancer stem cells: A driver for metastatic progression and target for antimetastatic cancer therapy

Koichi Ito, Selda Onturk, Katie Powell, Beatrice Philip, James S. Wilmott, Richard A Scolyer, Peter Hersey, Stephen J. Ralph

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Abstract 2609: Hypoxia-mediated downregulation of GCNT2/I-antigen in metastatic melanoma accelerates disease progression and mortality

Asmi Chakraborty, Mariana Perez, Norhan Mohammed, Michael Wells, James S. Wilmott, John F. Thompson, Stuart M. Haslam, Wei Wang, Richard A Scolyer, Gëorge F. Murphy, Charles J. Dimitroff

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Water‐Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase

Jerome M. Fox, Kyungtae Kang, M. C. Shamanthaka Sastry, Woody Sherman, Banumathi Sankaran, Peter H. Zwart, George M M Whitesides

Hypoxia Controls the Glycome Signature and Galectin-8–Ligand Axis to Promote Protumorigenic Properties of Metastatic Melanoma

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Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma

Correction: Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma

Abstract B8: Galectin-1 expressed in human melanoma is bound to cancer stem cells: A driver for metastatic progression and target for antimetastatic cancer therapy

Abstract 2609: Hypoxia-mediated downregulation of GCNT2/I-antigen in metastatic melanoma accelerates disease progression and mortality

Water‐Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase