Hyperphosphorylated Tau Induces Cortical Hypoexcitability in Transgenic Mouse Models: A Meta-Analysis

Carlos Antonio García-Carlos; Gustavo Basurto‐Islas; George Perry; Siddhartha Mondragón‐Rodríguez

doi:10.31083/jin39192

Abstract

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In this analysis, we uncovered that neuronal oscillations in cortical networks are altered from the prodromal to late stages of pathology. Additionally, we found that hyperphosphorylated tau accumulation is strongly associated with cortical network hypoexcitability in tau transgenic models.

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