Hybrid Alginate‐Based Cryogels for Life Science Applications
Article 2016 en
Authors
AB
Alexandre A. Barros
SQ
Sakeena Quraishi
MM
Marta Martins
Abstract
1 min read
Abstract This work presents a novel route toward porous scaffolds for tissue engineering and regenerative medicine (TERM) applications. Hybrid cryogels with gelatin, gellan gum, carboxymethylcellulose, and lignin were prepared by a two‐step process. Textural properties of the cryogels were analyzed by SEM and micro‐computed tomography. The results indicated that rapid freezing retained sample shape and yielded macroporous materials. The mechanical properties of the cryogels were characterized in compression mode. Cytotoxicity studies indicated that the hybrid‐alginate cryogels did not present cytotoxicity and have the potential to be used in TERM.
Nuno A. Silva, António J. Salgado, Rui A. Sousa, João Tiago Oliveira, A. J. Pedro, Hugo Leite‐Almeida, Rui Cerqueira, Armando Almeida, Fabrizio G. Mastronardi, João F. Mano, Nuno M. Neves, Nuno Sousa, Rui L Reis
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