Human Herpesvirus 8 Gene Encodes a Functional Thymidylate Synthase

Gábor Gáspár; De Clercq Erik; Johan Neyts

doi:10.1128/jvi.76.20.10530-10532.2002

Abstract

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We demonstrate that human herpesvirus 8, obtained from the lymphoma cell line BC-3 as well as from Kaposi's sarcoma lesions, carries a gene that encodes a functional thymidylate synthase (TS). The particular characteristics of this enzyme are studied and compared to the characteristics of TSs encoded by other organisms.

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