Interleukin-1 (IL-1) belongs to a family of cell activators termed cytokines. These are proteins which mediate the activation, differentiation or maturation of cells involved in immune and inflammatory responses [reviewed in 1]. The advent of cytokines has allowed elaborate networks to be established between a wide variety of cell types. This has greatly improved our understanding of the molecular and cellular events which occur during inflammation.
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Carla Zoja, Jiming Wang, S Bettoni, Marina Sironi, Daniela Renzi, Francesça Chiaffarino, Hanna E. Abboud, Jo Van Damme, Alberto Mantovani, Giuseppe Remuzzi
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