HIV infection results in ventral–striatal reward system hypo-activation during cue processing

Stefan S. du Plessis; Matthijs Vink; John A. Joska; Eleni Koutsilieri; Asif Bagadia; Dan Joseph Stein; Robin Emsley

doi:10.1097/qad.0000000000000680

Abstract

1 min read

HIV caused a decrease in activity during cue processing in the ventral striatum, with normal cortical functioning during reward outcome processing. Our results therefore suggest that HIV not only has an impact on fronto-striatal systems involved in executive functioning, but also has a direct impact on the function of the ventral-striatal reward system.

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