Histamine Receptor H1–Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome

Mira M. Wouters; Dafne Balemans; Sander Van Wanrooy; James Dooley; Vincent Cibert‐Goton; Yeranddy A. Alpízar; Eduardo E. Valdez-Moráles; Yasmin Nasser; Paul P. Van Veldhoven; Winde Vanbrabant; Van der Merwe; Raf Mols; Bart Ghesquière; Carla Cirillo; Inge Kortekaas Krohn; Peter Carmeliet; Willy Peetermans; Séverine Vermeire; Paul Rutgeerts; Patrick Augustijns; Peter W. Hellings; Ann Belmans; Stephen Vanner; David C. Bulmer; Karel Talavera; Pieter Vanden Berghe; Adrian Liston; Guy E. Boeckxstaens

doi:10.1053/j.gastro.2015.12.034

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Histamine Receptor H1–Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome

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