Higher Trough Vedolizumab Concentrations During Maintenance Therapy are Associated With Corticosteroid-Free Remission in Inflammatory Bowel Disease

Ryan C. Ungaro; Andrés Yarur; Jacqueline Jossen; Becky L. Phan; Ezra Chefitz; Priya Sehgal; Kanika Kamal; Alexandra Bruss; Poonam Beniwal‐Patel; Caroline S. Fox; Amir Patel; Bayda Bahur; Anjali Jain; Dan Joseph Stein; Snehal Naik; Marla C. Dubinsky

doi:10.1093/ecco-jcc/jjz041

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Higher Trough Vedolizumab Concentrations During Maintenance Therapy are Associated With Corticosteroid-Free Remission in Inflammatory Bowel Disease

Article 2019 en

Abstract

1 min read

In a large real-world cohort of vedolizumab maintenance concentrations, IBD patients with remission defined by objective measures [CRP and endoscopy] had significantly higher trough vedolizumab concentrations and immunogenicity was uncommon.

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