We consider resting-state Functional Magnetic Resonance Imaging (fMRI) of two classes of patients: one that took the drug N-acetylcysteine (NAC) and the other one a placebo before and after a smoking cessation treatment. Our goal was to classify the relapse in nicotine-dependent patients as treatment or non-treatment based on their fMRI scans. 80% accuracy was obtained using Independent Component Analysis (ICA) along with Genetic Programming (GP) classifier using High Performance Computing (HPC) which we consider significant enough to suggest that there is a difference in the resting-state fMRI images of a smoker that undergoes this smoking cessation treatment compared to a smoker that receives a placebo.
Prakaykaew Charunwatthana, Maryam Faiz, Ronnatrai Ruangveerayut, Richard J. Maude, Mushfiqur Rahman, L. Jackson Roberts, Kevin Moore, Emran Bin Yunus, M. Gofranul Hoque, Mahatab Uddin Hasan, Sue J. Lee, Sasithon Pukrittayakamee, Paul N. Newton, Sir Nicholas White, Nicholas Day, Arjen M. Dondorp
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