High-level semi-synthetic production of the potent antimalarial artemisinin

Christopher J. Paddon; Patrick J. Westfall; Douglas J. Pitera; Kirsten R. Benjamin; Karl J. Fisher; Derek McPhee; Michael D. Leavell; Anna Tai; A. Denise Main; Diana G. Eng; Devin R. Polichuk; Keat H. Teoh; Darwin W. Reed; T. Treynor; Jacob R. Lenihan; Hanxiao Jiang; Martin Fleck; Sunil Bajad; G. Dang; D. Dengrove; Don Diola; G. Dorin; Kenneth W. Ellens; Scott Fickes; Jorge L. Galazzo; Sara P. Gaucher; T. Geistlinger; Roselani I. Henry; M. Hepp; Tizita Horning; Talat Iqbal; Lance Kizer; Bonny Lieu; David J. Melis; Nathan A. Moss; Rika Regentin; S. Secrest; Hiroko Tsuruta; Raúl Vázquez López; Lars F. Westblade; Lan Xu; Min Yu; Y. Zhang; L. Zhao; Jeff Lievense; Patrick S. Covello; Jay D Keasling; K. K. Reiling; Neil S. Renninger; Jonathan Newman

doi:10.1038/nature12051

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