High-Level Production of Amorpha-4,11-Diene, a Precursor of the Antimalarial Agent Artemisinin, in Escherichia coli — Hiroko Tsuruta (2009) | RDL Network
High-Level Production of Amorpha-4,11-Diene, a Precursor of the Antimalarial Agent Artemisinin, in Escherichia coli
Article 2009 en
Authors
HT
Hiroko Tsuruta
CP
Christopher J. Paddon
DE
Diana G. Eng
Abstract
1 min read
Production of >25 g/L amorpha-4,11-diene by fermentation followed by chemical conversion to artemisinin may allow for development of a process to provide an alternative source of artemisinin to be incorporated into ACTs.
Patrick J. Westfall, Douglas J. Pitera, Jacob R. Lenihan, Diana G. Eng, Frank X. Woolard, Rika Regentin, Tizita Horning, Hiroko Tsuruta, David J. Melis, Andrew E. Owens, Scott Fickes, Don Diola, Kirsten R. Benjamin, Jay D Keasling, Michael D. Leavell, Derek McPhee, Neil S. Renninger, Jack D. Newman, Christopher J. Paddon
Discussion(0)
No comments yet. Be the first to comment.