HIF-1α dependent metabolic reprogramming of periosteal cells improves bone repair

Steve Stegen; Nick van Gastel; Guy Eelen; Annelies Quaegebeur; Riet Van Looveren; Peter Carmeliet; Geert Carmeliet

Related publications

Article2011

Metabolic reprogramming by HIF-1 promotes the survival of bone marrow–derived angiogenic cells in ischemic tissue

Sergio Rey, Weibo Luo, Larissa A. Shimoda, Gregg L. Friedman

Article2017

Hypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism

A. A. Roger Thompson, Rebecca Dickinson, Fiona Murphy, John P. Thomson, Helen M. Marriott, Adriana Tavares, Joseph Willson, Lynne Williams, Amy Lewis, Ananda S. Mirchandani, Patricia Dos Santos Coelho, Catherine Doherty, Eilíse M. Ryan, Emily Watts, Nicholas M. Morton, Shareen Forbes, Roland H. Stimson, Abdul Hameed, Nadine Arnold, Julie A. Preston, Allan Lawrie, Veronica Finisguerra, Massimiliano Mazzone, Pranvera Sadiku, Jermaine Goveia, Federico Taverna, Peter Carmeliet, Simon J. Foster, Edwin R. Chilvers, Andrew S. Cowburn, David H. Dockrell, Randall S. Johnson, Richard R. Meehan, Moira K. B. Whyte, Sarah R. Walmsley

Article2013

Preconditioning periosteal cells by inactivation of the Phd2 oxygen sensor improves their bone forming capacity in a large segmental bone defect

Steve Stegen, Nick van Gastel, Riet Van Looveren, Frank P. Luyten, Peter Carmeliet, Geert Carmeliet

Article2013

Combination of HIF-1α gene transfection and HIF-1-activated bone marrow-derived angiogenic cell infusion improves burn wound healing in aged mice

Jiajun Du, Lu Liu, Frank Lay, Q Wang, Chang-Xin Dou, X Zhang, Sayed Mohammad Hosseini, Andrew D. Simon, D. Jasper G. Rees, Ali Ahmed, Roopa Sebastian, Kakali Sarkar, Stephen J. Milner, Guy P. Marti, Gregg L. Friedman, John W. Harmon

Article2012

Preconditioning mouse periosteal cells to hypoxia by inactivation of the Phd2 oxygen sensor improves in vivo ectopic bone formation

Steve Stegen, Nick van Gastel, Riet Van Looveren, Peter Carmeliet, Frank P. Luyten, Geert Carmeliet