Heritability of Atrial Fibrillation

Genetic variation contributes substantially to AF risk. The risk for AF conferred by genomic variation is similar to that observed for several other cardiovascular diseases. Established AF loci only explain a moderate proportion of disease risk, suggesting that further genetic discovery, with an emphasis on common variation, is warranted to understand the causal genetic basis of AF.

Discussion(0)

No comments yet. Be the first to comment.

Publication Info

DOI: 10.1161/circgenetics.117.001838
Year: 2017
Published: —
Language: en

Article Details

Volume: 10
Issue: 6
Link Of The Paper: https://doi.org/10.1161/circgenetics.117.001838

Timeline

Created:June 19, 2026

Related publications

Article2017

Abstract P100: Heritability of Atrial Fibrillation

Lu‐Chen Weng, Seung Hoan Choi, Derek Klarin, Po−Ru Loh, Mark Chaffin, Carolina Roselli, Olivia Hulme, J. G. Smith, Sekar Kathiresan, Kathryn L. Lunetta, Josée Dupuis, Chris Newton-Cheh, Emelia Benjamin, Patrick T. Ellinor, Steven A. Lubitz

Article2016

Whole Exome Sequencing in Atrial Fibrillation

Steven A. Lubitz, Jennifer A. Brody, Nathan A. Bihlmeyer, Carolina Roselli, Lu‐Chen Weng, Ingrid E. Christophersen, Álvaro Alonso, Eric Boerwinkle, Richard A. Gibbs, Joshua C. Bis, L. Adrienne Cupples, Peter J. Mohler, Deborah A. Nickerson, Donna M. Muzny, Marco Pérez, Bruce M. Psaty, Elsayed Z. Soliman, Nona Sotoodehnia, Kathryn L. Lunetta, Emelia Benjamin, Susan R. Heckbert, Dan E. Arking, Patrick T. Ellinor, Honghuang Lin

Article2016

Genetic Risk Prediction of Atrial Fibrillation

Steven A. Lubitz, Xiaoyan Yin, Henry J. Lin, Matthew J. Kolek, J. G. Smith, Stella Trompet, Michiel Rienstra, Natalia S. Rost, Pedro L. Teixeira, Peter Almgren, Christopher D. Anderson, Lin Y. Chen, Gunnar Engström, Ian Ford, Karen L. Furie, Xiuqing Guo, Martin G. Larson, Kathryn L. Lunetta, Peter W. Macfarlane, Bruce M. Psaty, Elsayed Z. Soliman, Nona Sotoodehnia, David J. Stott, Kent D. Taylor, Lu‐Chen Weng, Jie Yao,

Preprint2017

Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

Sara L. Pulit, Lu‐Chen Weng, Patrick F. McArdle, Ludovic Trinquart, Seung Hoan Choi, Braxton D. Mitchell, Jonathan Rosand, P. Bakker, Emelia Benjamin, Patrick T. Ellinor, Steven J. Kittner, Steven A. Lubitz, Christopher D. Anderson, Ingrid E. Christophersen, Michiel Rienstra, Carolina Roselli, Xiaoyan Yin, Bastiaan Geelhoed, John Barnard, Honghuang Lin, Dan E. Arking, Albert V. Smith, Christine M. Albert,

Article2017

Atrial Fibrillation

Laila Stærk, Jason A. Sherer, Darae Ko, Emelia Benjamin, Robert Helm

Bastiaan Geelhoed,

Niek Verweij,

Joylene E. Siland,

Sekar Kathiresan,

Carolina Roselli,

Dan M. Roden,

Pim van der Harst,

Dawood Darbar,

J. Wouter Jukema,

Olle Melander,

Jonathan Rosand,

Jerome I. Rotter,

Susan R. Heckbert,

Patrick T. Ellinor,

Álvaro Alonso,

Emelia Benjamin

Mark Chaffin,

Nathan R. Tucker,

Molong Li,

Derek Klarin,

Nathan A. Bihlmeyer,

Siew‐Kee Low,

Peter Weeke,

Martina Müller‐Nurasyid,

J. G. Smith,

Jennifer A. Brody,

Maartje N. Niemeijer,

Marcus Dörr,

Stella Trompet,

Jennifer E. Huffman,

Stefan Gustafsson,

Claudia Schurmann,

Marcus E. Kleber,

Leo‐Pekka Lyytikäinen,

Ilkka Seppälä,

Rainer Malik,

A.R.V.R. Horimoto,

Marco Pérez,

Juha Sinisalo,

Stefanie Aeschbacher,

Sébastien Thériault,

Jie Yao,

Farid Radmanesh,

Stefan Weiß,

Alexander Teumer,

Seung Hoan Choi,

Lu‐Chen Weng,

Sebastian Clauß,

Rajat Deo,

Daniel J. Rader,

Svati Shah,

Joylene E. Siland,

Michiaki Kubo,

Jonathan D. Smith,

David R. Van Wagoner,

Joshua C. Bis,

Siegfried Perz,

Bruce M. Psaty,

Paul M. Ridker,

Jared W. Magnani,

Tamara B. Harris,

Lenore J. Launer,

M. Benjamin Shoemaker,

Sandosh Padmanabhan,

Jeffrey Haessler,

Traci M. Bartz,

Mélanie Waldenberger,

Peter Lichtner,

Marina Arendt,

José Eduardo Krieger,

Mika Kähönen,

Lorenz Risch,

Alfredo José Mansur,

Annette Peters,

Blair H. Smith,

Lars Lind,

Stuart A. Scott,

Yingchang Lu,

Erwin B. Bottinger,

Jussi Hernesniemi,

Cecilia M. Lindgren,

Jorge Wong,

Jie Huang,

Markku Eskola,

Andrew P. Morris,

Ian Ford,

Alex P. Reiner,

Graciela Delgado,

Lin Y. Chen,

Yii‐Der Ida Chen,

Roopinder K. Sandhu,

Man Li,

Eric Boerwinkle