Royal Brompton Grand RoundsHeart-lung transplantation for cystic fibrosis Can be successful despite contraindications About 6500 people in Britain have cystic fibrosis and only half of patients reach 19 years of age.'Despite recent improvements in treatment there is still a considerable morbidity and mortality.2The main cause of death is respiratory failure from chronic respiratory infection.Heart-lung transplantation for cystic fibrosis was first successfully carried out in 1985, and over 100 patients have now received transplants in Britain.34Case history A 29 year old man-had had cystic fibrosis c at the age of 4 years when he presented v absorption.At 14 years he had developed Royal Brompton National chest infections.Clinical treatment con, Heart and Lung Hospital, pancreatic enzymes, vitamins, chest physi London SW3 6HP antibiotics, and bronchodilators.In 1975 he I left abrasion pleurodesis and in 1981 a right Case presented by: pleurodesis for recurrent pneumothoraces.H(
Karin M. de Winter-de Groot, Hettie M. Janssens, Rick T. van Uum, Johanna F. Dekkers, Gitte Berkers, Annelotte M. Vonk, Evelien Kruisselbrink, Hugo Oppelaar, Robert G.J. Vries, Hans Clevers, Roderick H.J. Houwen, Johanna C. Escher, Sjoerd G. Elias, Hugo R de Jonge, Yolanda B. de Rijke, Harm A.W.M. Tiddens, Cornelis K. van der Ent, Jeffrey M. Beekman
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