Gut microbiota remodelling alleviates elderly sepsis by microbiota-derived acetic acid via FFAR2/NLRP3 pathway

Guangwei Yu; Wenhui Xie; Jingnan Xiang; Yilang Ke; Zhong Lin Wang; Fuquan Tu; Wenwei Wu; Huashan Hong; Xiaohong Lin

doi:10.1016/j.ejphar.2025.178229

Abstract

1 min read

Gut microbiota remodelling improves elderly sepsis via acetic acid, which can inhibit inflammatory reactions to alleviate myocardial damage by FFAR2/NLRP3 inflammasome inactivation.

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