Gut–microbiota–microglia–brain interactions in Alzheimer’s disease: knowledge-based, multi-dimensional characterization

QuanQiu Wang; Pamela B. Davis; Xin Qi; Shu G. Chen; Mark E. Gurney; George Perry; P. Murali Doraiswamy; Rong Xu

doi:10.1186/s13195-021-00917-1

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Gut–microbiota–microglia–brain interactions in Alzheimer’s disease: knowledge-based, multi-dimensional characterization

Article 2021 en

Abstract

1 min read

Our analysis produces a novel framework to offer insights into the mechanistic links between gut microbial metabolites, microglia, and AD, with the overall goal to facilitate disease mechanism understanding, therapeutic target identification, and designing confirmatory experimental studies.

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