Guidelines for the diagnosis and management of intrahepatic cholangiocarcinoma

John Bridgewater; Peter R. Galle; Shahid A. Khan; Josep M. Llovet; Joong‐Won Park; Tushar Patel; Timothy M. Pawlik; Gregory J. Gores

doi:10.1016/j.jhep.2014.01.021

Guidelines for the diagnosis and management of intrahepatic cholangiocarcinoma

Journal of Hepatology 60(6): 1268-1289

Article 2014 English

Abstract

1 min read

Cholangiocarcinoma (CCA) comprises a heterogeneous group of cancers with pathologic features of biliary tract differentiation, and is presumed to arise from the intra- or extrahepatic biliary tract. Two recent papers suggest these cancers may also arise directly from transdifferentiation of hepatocytes [1,2]. Gallbladder cancer is distinct from cholangiocarcinoma in epidemiology, pathobiology, clinical presentation and management, and should be considered a different form of biliary tract cancer [3].

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