Graves’ Disease, Rheumatoid Arthritis, and Anti-Tumor Necrosis Factor-α Therapy

We read with interest the letter by van Lieshout, et al 1, describing a 70-year-old woman who developed Graves' disease while being treated with anti-tumor necrosis factor-α (anti-TNF-α; adalimumab) for active rheumatoid arthritis (RA). They suggested an association of autoimmune thyroid disease with various autoimmune diseases including RA, but could not conclude whether there … Address reprint requests to Dr. J.S. Lee, Department of Pediatrics, Yonsei University College of Medicine, 250 Sungsan-Ro, Seodaemun-Ku, 120-752, CPO Box 8044, Seoul, Korea. E-mail: jsyonse{at}yuhs.ac