Remarkable progress has been made in the past two years in the investigation of immunological events and effector mechanisms which lead to glomerular inflammation and tissue damage, suggesting a number of areas in which therapeutic modulation is possible. We review recent advances in the two major areas of investigation in this field: the nephritogenic response to glomerulonephritis and local inflammatory reaction, and the novel therapeutic perspectives that have emerged from insights into the biology and pathology of the immune and inflammatory response.
Shaun A. Summers, Oliver M. Steinmetz, Joshua D. Ooi, Poh‐Yi Gan, Kim M. O’Sullivan, Kumar Visvanathan, Akira Shizuo, A. Richard Kitching, Stephen R. Holdsworth
A. Richard Kitching, Amanda Turner, Gabrielle R. Wilson, Timothy Semple, Dragana Odobasic, Jennifer R. Timoshanko, Kim M. O’Sullivan, Peter G. Tipping, Kiyoshi Takeda, Akira Shizuo, Stephen R. Holdsworth
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