Global utilization of low-dose corticosteroids in severe sepsis and septic shock: a report from the PROGRESS registry

Richard Beale; Jonathan Janes; Frank M. Brunkhorst; Geoffrey Dobb; Mitchell M. Levy; Greg S. Martin; Graham Ramsay; Eliezer Silva; Charles L. Sprung; B. Vallet; Jean Louis Vincent; Timothy M. Costigan; Amy G Leishman; Mark D. Williams; Konrad Reinhart

doi:10.1186/cc9044

Abstract

1 min read

Widespread use of LDC for the treatment of severe sepsis with significant regional and country variation exists. In this study, 14.2% of patients received LDC despite the absence of evidence of shock. Hospital mortality was higher in the LDC group and remained higher after adjustment for key determinates of mortality.

Related publications

Article2010

Revisiting the loading dose of amikacin for patients with severe sepsis and septic shock

Fabio Silvio Taccone, Pierre‐François Laterre, Herbert Spapen, Thierry Dugernier, Isabelle Delattre, Brice Layeux, Daniel De Backer, Xavier Wittebole, Pierre Wallemacq, Jean Louis Vincent, Frédérique Jacobs

Article2004

Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock

R. Phillip Dellinger, Jean Carlet, Henry Masur, Herwig Gerlach, Thierry Calandra, Jonathan Cohen, Juan Gea‐Banacloche, Didier Keh, John C. Marshall, Margaret M. Parker, Graham Ramsay, Janice L. Zimmerman, Jean Louis Vincent, Mitchell M. Levy

Article2008

Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008

R. Phillip Dellinger, Mitchell M. Levy, Jean Carlet, Julian Bion, Margaret M. Parker, Roman Jaeschke, Konrad Reinhart, Derek C. Angus, Christian Brun‐Buisson, Richard Beale, Thierry Calandra, Jean-François Dhainaut, Herwig Gerlach, Maurene A. Harvey, John J. Marini, John C. Marshall, Marco Ranieri, Graham Ramsay, Jonathan Sevransky, Bruce Thompson, Sean R. Townsend, Jeffrey S. Vender, Janice L. Zimmerman,

Article2010

Researchβ-lactam concentrations in the early phase of severe sepsis and septic shock

Fabio Silvio Taccone, Pierre‐François Laterre, Thierry Dugernier, Herbert Spapen, Isabelle Delattre, Xavier Wittebole, Daniel De Backer, Brice Layeux, Pierre Wallemacq, Jean Louis Vincent, Frédérique Jacobs

Article2011

Type of fluid in severe sepsis and septic shock.

Jean Louis Vincent, Leonardo Gottin