Genomic Variation Associated With Mortality Among Adults of European and African Ancestry With Heart Failure: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

Joshua C. Bis; Ying A. Wang; L. Adrienne Cupples; Patricia P. Chang; James T. Willerson; Eric Boerwinkle; Nicole L. Glazer; Emelia Benjamin; Kenneth Rice; Ervin R. Fox; Jacqueline C.M. Witteman; Alanna C. Morrison; Nicholas L. Smith; Talin Haritunians; Bruno H. Stricker; André G. Uitterlinden; Bruce M. Psaty; Abbas Dehghan; Thomas Lumley; Laura R. Loehr; Christopher J. O’Donnell; Wayne D. Rosamond; Daniel Levy; Aaron R. Folsom; Yurii S. Aulchenko; Fernando Rivadeneira; Janine F. Felix; Ramachandran S. Vasan; David Couper; Jerome I. Rotter; Thomas J. Wang; Albert Hofman; Serkalem Demissie; Cornelia M. van Duijn

doi:10.17615/4tec-rx52

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Emelia Benjamin

Genomic Variation Associated With Mortality Among Adults of European and African Ancestry With Heart Failure: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

Article 2020 en

Authors

JB
Joshua C. Bis
YW
Ying A. Wang
LC
L. Adrienne Cupples

Abstract

1 min read

Prognosis and survival are significant concerns for individuals with heart failure (HF). In order to better understand the pathophysiology of HF prognosis, the association between 2,366,858 single nucleotide polymorphisms (SNPs) and all-cause mortality was evaluated among individuals with incident HF from four community-based prospective cohorts: the Atherosclerosis Risk in Communities Study, the Cardiovascular Health Study, the Framingham Heart Study, and the Rotterdam Study.

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