Genetic interaction between placental growth factor and vascular endothelial growth factor A in psoriasis

Helen Young; Ian Kamaly-Asl; Philip Laws; P. Pemberton; Christopher Em Griffiths

doi:10.1111/ced.14102

Abstract

1 min read

Our observed genetic interaction between PGF and VEGFA appears relevant to psoriasis, a disease with an angiogenic basis, and may influence development of an antiangiogenic approach to treatment.

Discussion(0)

No comments yet. Be the first to comment.

Related publications

Article2017

Influences of placental growth factor on mouse retinal vascular development

Vanessa R. Kay, Chandrakant Tayade, Peter Carmeliet, B. Anne Croy

Article1999

Levels of endothelial cell stimulating angiogenesis factor and vascular endothelial growth factor are elevated in psoriasis

M. Bhushan, B. McLaughlin, J B Weiss, Christopher Em Griffiths

Article2013

Role of vascular endothelial growth factor in the pathophysiology of nonalcoholic steatohepatitis in two rodent models

Stéphanie Coulon, Vanessa Legry, Femke Heindryckx, Christophe Van Steenkiste, Christophe Casteleyn, Kim Olievier, Louis Libbrecht, Peter Carmeliet, Bart Jonckx, Jean–Marie Stassen, Hans Van Vlierberghe, Isabelle Leclercq, Isabelle Colle, Anja Geerts

Article2009

Genetic susceptibility to psoriasis: an emerging picture

Rhodri Smith, Richard B. Warren, Christopher Em Griffiths, Jane Worthington

Article2018

Effects of placental growth factor deficiency on behavior, neuroanatomy, and cerebrovasculature of mice

Vanessa R. Kay, Matthew T. Rätsep, Lindsay S. Cahill, Andrew F. Hickman, Bruno Zavan, Margaret E. Newport, Jacob Ellegood, Christine Laliberté, James N. Reynolds, Peter Carmeliet, Chandrakant Tayade, John G. Sled, B. Anne Croy