Generation of Hot Spots with Silver Nanocubes for Single‐Molecule Detection by Surface‐Enhanced Raman Scattering

Getting hotter: Hot spots that enable detection of surface-enhanced Raman scattering (SERS) from a single molecule can form at the nanocube–substrate interface by simply depositing a silver nanocube onto a metal substrate (see picture). This new approach offers great simplicity for the formation of robust and fully accessible hot spots, thus providing an effective platform for ultrasensitive detection. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.