Gene-Expression Profiles in Hereditary Breast Cancer
Letter 2001 en
Authors
IH
Ingrid Hedenfalk
DD
David Duggan
YC
Y Chen
Abstract
1 min read
Many cases of hereditary breast cancer are due to mutations in either the BRCA1 or the BRCA2 gene. The histopathological changes in these cancers are often characteristic of the mutant gene. We hypothesized that the genes expressed by these two types of tumors are also distinctive, perhaps allowing us to identify cases of hereditary breast cancer on the basis of gene-expression profiles.
Tereza Vaclová, Nicholas T. Woods, Fernando Setién, José María García Bueno, José A. Macías, Alicia Barroso, Miguel Urioste, Manel Esteller, Álvaro N.A. Monteiro, Javier Benı́tez, Ana Osório
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