Gammaherpesviruses encode functional dihydrofolate reductase activity

Gábor Gáspár; De Clercq Erik; Johan Neyts

doi:10.1016/s0006-291x(02)02286-6

Related publications

Article2015

A nanotherapy strategy significantly enhances anticryptosporidial activity of an inhibitor of bifunctional thymidylate synthase-dihydrofolate reductase from Cryptosporidium

Anindita Mukerjee, Pinar Iyidogan, Alejandro Castellanos-González, José A. Cisneros, Daniel J. Czyzyk, Amalendu P. Ranjan, William L. Jorgensen, A. Clinton White, Jamboor K. Vishwanatha, Karen S. Anderson

Bioorganic & Medicinal Chemistry Letters

Article2009

Dihydrofolate reductase amplification and sensitization to methotrexate of methotrexate-resistant colon cancer cells

Cristina Morales, María J. García, Maria Ribas, Rosa Miró, Mar Muñoz, Carlos Caldas, aaa bbb

Article2002

Molecular characterization of dihydrofolate reductase in relation to antifolate resistance in Plasmodium vivax

Ubolsree Leartsakulpanich, Mallika Imwong, Sasithon Pukrittayakamee, Sir Nicholas White, Georges Snounou, Worachart Sirawaraporn, Yongyuth Yuthavong

Molecular and Biochemical Parasitology

Article2014

Virtual screening reveals allosteric inhibitors of the Toxoplasma gondii thymidylate synthase–dihydrofolate reductase

Hitesh Kumar Sharma, Mark J. Landau, Todd J. Sullivan, Vidya P. Kumar, Markus K. Dahlgren, William L. Jorgensen, Karen S. Anderson

Bioorganic & Medicinal Chemistry Letters

Article2003

Importance of Substrate and Cofactor Polarization in the Active Site of Dihydrofolate Reductase

Mireia Garcia‐Viloca, Donald G Truhlar, Jiali Gao