Gait impairments are ubiquitous in Alzheimer's disease (AD) and other dementias. Although the main clinical hallmark of dementia is cognitive impairment and decline [1], motor impairments, such as bradykinesia, extrapyramidal rigidity, and gait disorders, have been commonly described, mostly in late stages However, during the last two decades, large epidemiological studies have shown that gait disorders, particularly slowing gait, may be present at early stages of dementia or may even predict who will be at risk of progressing to dementia
Liu‐Yun Wu, Irwin K. Cheah, Joyce R. Chong, Yuek Ling Chai, Jia Yun Tan, Saima Hilal, Henri A. Vrooman, Christopher Chen, Barry Halliwell, Mitchell K.P. Lai
Akihiko Nunomura, Toshio Tamaoki, Nobutaka Motohashi, Masao Nakamura, Daniel W. McKeel, Massimo Tabaton, Hyoung‐gon Lee, Mark A. Smith, George Perry, Xiongwei Zhu
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