Functional Connectomics and Disease Progression in Drug‐Naïve Parkinson's Disease Patients

Rosa De Micco; Federica Agosta; Silvia Basaia; Mattia Siciliano; Camilla Cividini; Gioacchino Tedeschi; Massimo Filippi; Alessandro Tessitore

doi:10.1002/mds.28541

Abstract

1 min read

Our findings revealed that functional reorganization of the brain connectome occurs early in PD and underlies crucial involvement of striatal projections. Connectomic measures may be helpful to identify a specific PD patient subtype, characterized by severe motor and non-motor clinical burden as well as widespread functional connectivity abnormalities. © 2021 International Parkinson and Movement Disorder Society.

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