Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis

Zulma Ortiz; Beverley Shea; María E. Suarez‐Almazor; David Moher; George A. Wells; Peter Tugwell

doi:10.1002/14651858.cd000951

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Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis

Article 1999 en

Abstract

1 min read

The results support the protective effect of folate supplementation in reducing MTX side effects related to the oral and GI systems. We could not determine if folic was different from folinic acid. Therefore, for folinic acid to be considered cost-effective it must be found more effective than folic acid at reducing MTX side effects.

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