Focal Adhesion Kinase Is Required for Intestinal Regeneration and Tumorigenesis Downstream of Wnt/c-Myc Signaling

G H S Ashton; Jennifer P. Morton; Kevin Myant; Toby J. Phesse; Rachel A. Ridgway; Victoria Marsh; Julie A. Wilkins; Dimitris Athineos; Vanesa Muncan; Richard Kemp; Kristi L. Neufeld; Hans Clevers; Valerie G. Brunton; Douglas J. Winton; Xiaoyan Wang; Rosalie C. Sears; Alan R. Clarke; Margaret C. Frame; Owen J. Sansom

doi:10.1016/j.devcel.2025.05.001

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Focal Adhesion Kinase Is Required for Intestinal Regeneration and Tumorigenesis Downstream of Wnt/c-Myc Signaling

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ERK/MAPK signaling is essential for intestinal development through Wnt pathway modulation

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Data from Cyclin D2–Cyclin-Dependent Kinase 4/6 Is Required for Efficient Proliferation and Tumorigenesis following Apc Loss

Data from Cyclin D2–Cyclin-Dependent Kinase 4/6 Is Required for Efficient Proliferation and Tumorigenesis following Apc Loss