Five new diarylheptanoids from the rhizomes of Curcuma kwangsiensis and their antiproliferative activity

Five new diarylheptanoids (1–5), along with nine known ones (6–14), were isolated from the rhizomes of Curcuma kwangsiensis. Their structures were established on the basis of spectroscopic analyses. Compounds 1–3 were cyclic diarylheptanoids rarely discovered from C. kwangsiensis. Of all the isolated compounds, compound 4 showed moderate antiproliferative activity on HH and HaCaT cells.