Figure S5 from PD-L1 Negative Status is Associated with Lower Mutation Burden, Differential Expression of Immune-Related Genes, and Worse Survival in Stage III Melanoma

<p>Meta-analysis of TCGA classification clusters. A) Methylation classification clusters, and B) Mutation classification clusters, described by the cancer genome atlas network. The hypomethylated cluster is associated with PD-L1 positive status (p = 0.047; Fishers exact test). No significant correlations were found for mutation clusters, although the NF1 mutant cluster was restricted to PD-L1 positive tumors (p = 0.096; Fishers exact test).</p>