Figure S4 from ERBB4-Mediated Signaling Is a Mediator of Resistance to PI3K and BTK Inhibitors in B-cell Lymphoid Neoplasms

<p>(A) Heatmap of functionally annotated genes showing log2-scaled fold change and -log10 adjusted P-value (FDR) by RNA-seq comparing K1718 parental and resistant cells. (B) Gene set enrichment analyses (GSEA, Broad Institute) comparing parental and resistant per each line. Statistically significant differences with values of absolute NES higher than1, P <0.05 and FDR <0.25.</p>