FDA approves lurbinectedin in combination with atezolizumab for extensive-stage small cell lung cancer

Oliver Kepp; Guido Guido Kroemer

doi:10.1080/2162402x.2025.2584898

Abstract

1 min read

The recent FDA approval of lurbinectedin plus atezolizumab for advanced small cell lung cancer underscores the promise of combining immunogenic cell death (ICD) inducers with PD-1/PD-L1 blockade. This synergistic strategy induces durable responses in refractory tumors and may extend immunotherapy benefits across diverse malignancies through rational ICD-checkpoint inhibitor combinations.

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