Exploring the functional interaction between POSH and ALIX and the relevance to HIV-1 release
Article 2009 en
Authors
JV
Jörg Votteler
EI
Elena Iavnilovitch
OF
Orit Fingrut
Abstract
1 min read
Thus, the cumulative results identified ALIX as an ubiquitination substrate of POSH and indicate that POSH and ALIX cooperate to facilitate efficient virus release. However, while ALIX is obligatory for the release of YPXnL-dependent HIV-1, POSH, albeit rate-limiting, may be functionally interchangeable.
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