Evolution of the CRISPR-Cas adaptive immunity systems in prokaryotes: models and observations on virus–host coevolution

Eugene V Koonin; Yuri I. Wolf

doi:10.1039/c4mb00438h

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Evolution of the CRISPR-Cas adaptive immunity systems in prokaryotes: models and observations on virus–host coevolution

Article 2014 en

Abstract

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Mathematical modeling of the coevolution of CRISPR-Cas, the prokaryotic heritable adaptive immunity system, with viruses yields many non-trivial, testable predictions.

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