Establishment of human fetal hepatocyte organoids and CRISPR–Cas9-based gene knockin and knockout in organoid cultures from human liver

Delilah Hendriks; Benedetta Artegiani; Huili Hu; Susana M. Chuva de Sousa Lopes; Hans Clevers

doi:10.1038/s41596-020-00411-2

Related publications

Article2023

Development of Plasmodium falciparum liver-stages in hepatocytes derived from human fetal liver organoid cultures

Annie S. P. Yang, Devanjali Dutta, Kai Kretzschmar, Delilah Hendriks, Jens Puschhof, Huili Hu, Kim E Boonekamp, Youri van Waardenburg, Susana M. Chuva de Sousa Lopes, Geert-Jan van Gemert, Johannes H.W. de Wilt, Teun Bousema, Hans Clevers, Robert W. Sauerwein, Annie S. P. Yang, Devanjali Dutta, Kai Kretzschmar, Delilah Hendriks, Jens Puschhof, Huili Hu, Kim E Boonekamp, Youri van Waardenburg, Susana M. Chuva de Sousa Lopes, Geert-Jan van Gemert, Johannes H.W. de Wilt, Teun Bousema, Hans Clevers, Robert W. Sauerwein

Article2016

Establishment of human fetal hepatocyte organoids and CRISPR–Cas9-based gene knockin and knockout in organoid cultures from human liver

Discussion(0)

Related publications

Development of Plasmodium falciparum liver-stages in hepatocytes derived from human fetal liver organoid cultures

DNA-free two-gene knockout in Chlamydomonas reinhardtii via CRISPR-Cas9 ribonucleoproteins

Differentiation and CRISPR-Cas9-mediated genetic engineering of human intestinal organoids

Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis

Modeling Breast Cancer Using CRISPR-Cas9–Mediated Engineering of Human Breast Organoids