Erythropoietic Response and Outcomes in Kidney Disease and Type 2 Diabetes
Article 2010 en
Authors
SS
Scott D. Solomon
HU
Hajime Uno
EL
Eldrin F. Lewis
Abstract
1 min read
A poor initial hematopoietic response to darbepoetin alfa was associated with an increased subsequent risk of death or cardiovascular events as doses were escalated to meet target hemoglobin levels. Although the mechanism of this differential effect is not known, these findings raise concern about current target-based strategies for treating anemia in patients with chronic kidney disease. (Funded by Amgen; ClinicalTrials.gov number, NCT00093015.)
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