Epigenetic profiling identifies MIR10A-5 p as a putative tumor suppresor in Ewing sarcoma and rhabdomyosarcoma
Article 2016 en
Authors
DM
D. Perez Martin
FC
Frank Court
SR
Santiago Rello‐Varona
Abstract
1 min read
Introduction: Aberrant DNA methylation is thought to be closely related to the development of cancer. Therefore, the identification of specific DNA methylation markers in Ewing sarcoma (ES) and Rhabdomyosarcoma (RMS) would be helpful for understanding the pathogenetic mechanism as well as for developing new therapies. We analyzed the methylome of ES and RMS tumors and cell lines.
David Herrero‐Martín, Franck Court, Santiago Rello‐Varona, Miguel Sáinz‐Jaspeado, Raquel Buj, Sebastián Morán, Sílvia García-Monclús, Juan Huertas-Martínez, Jaume Mora, Miguel A. Peinado, Javier Alonso, Enrique de Álava, Dave Monk, Manel Esteller, Òscar M. Tirado
Giselle L. Saulnier Sholler, Dan G. Duda, Genevieve Bergendahl, David H. Ebb, Matija Snuderl, Theodore W. Laetsch, Jennifer Michlitsch, Derek Hanson, Michael S. Isakoff, Kevin Bielamowicz, Jacquline Kraveka, Peter Carmeliet, A. De Deene, Rakesh K. Jain
Juan Huertas-Martínez, Santiago Rello‐Varona, David Herrero‐Martín, Ignasi Barrau, Sílvia García-Monclús, Miguel Sáinz‐Jaspeado, Laura Lagares‐Tena, Yaiza Núñez‐Álvarez, Silvia Mateo‐Lozano, Jaume Mora, Josep Roma, Núria Torán, Sebastián Morán, Roser López‐Alemany, Soledad Gallego, Manel Esteller, Miguel A. Peinado, Xavier García del Muro, Òscar M. Tirado
Juan Huertas-Martínez, Ignasi Barrau, Miguel Sáinz‐Jaspeado, Laura Lagares‐Tena, Silvia Mateo‐Lozano, Jaume Mora, Josep Roma, Soledad Gallego, Sebastián Morán, Manel Esteller, Xavier García del Muro, Òscar M. Tirado
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