Enhanced corticotropin response to corticotropin-releasing hormone as a predictor of mania in euthymic bipolar patients

Eduard Vieta; M. J. MARTÍNEZ-DE-OSABA; Francesc Colom; Anabel Martínez‐Arán; Antonio Benabarre; Cristòbal Gastó

doi:10.1017/s0033291799008727

Abstract

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Bipolar patients in remission show mild abnormalities in ACTH levels before and after CRH stimulation. CRH challenge may be a potentially good predictor of manic or hypomanic relapse in remitted bipolar patients.

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