Engineering cartilage like tissue using polymeric systems derived from 2-ethyl-2-pyrrolidone-methacrylate combined with hyaluronic acid

Hydrogels are potential candidates for Tissue engineering (TE), because of their water content, transport properties, and tissue like physical and chemical behaviour. This project was based on the production and characterization of implantable stimuli responsive scaffolds made of hyaluronic acid (HA) that presents a high water retention character, in combination with 2-ethyl (2-pyrrolidone) methacrylate (EPM), possessing temperature-dependent solubility in water, by bulk polymerization. [...]