Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis

Delilah Hendriks; Jos F. Brouwers; Karien M. Hamer; Maarten H. Geurts; Léa Luciana; Simone Massalini; Carmen López‐Iglesias; Peter J. Peters; Maria J. Rodríguez Colman; Susana M. Chuva de Sousa Lopes; Benedetta Artegiani; Hans Clevers

doi:10.1038/s41587-023-01680-4

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Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis

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