Enantioselective fluorination of homoallylic alcohols enabled by the tuning of non-covalent interactions

Jaime A. S. Coelho; Akira Matsumoto; Manuel Orlandi; Margaret J. Hilton; Matthew S. Sigman; Dean Toste

doi:10.1039/c8sc02223b

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Enantioselective fluorination of homoallylic alcohols enabled by the tuning of non-covalent interactions

Article 2018 en

Abstract

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Multivariate correlation analysis, including designer π-interaction derived parameters, was applied to the study of the enantioselective fluorination of homoallylic alcohols <italic>via</italic> chiral anion phase transfer (CAPT) catalysis.

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