Elucidating Carfilzomib’s Induced Cardiotoxicity in an In Vivo Model of Aging: Prophylactic Potential of Metformin — Panagiotis Efentakis (2021) | RDL Network
Elucidating Carfilzomib’s Induced Cardiotoxicity in an In Vivo Model of Aging: Prophylactic Potential of Metformin
Article 2021 en
Authors
PE
Panagiotis Efentakis
GP
Garyfalia Psarakou
AV
Aimilia Varela
Abstract
1 min read
Carfilzomib induced cardiotoxicity in aged mice, an effect significantly reversed by metformin. The latter possesses translational importance as it further supports the clinical use of metformin as a potent prophylactic therapy.
Garyfallia Psarrakou, Michael Chatzistefanou, Panagiotis Efentakis, Aimilia Varela, Eleni‐Dimitra Papanagnou, Panagiota Nikolaou, Maria Tsoumani, Constantinos H. Davos, Efstathios Kastritis, Ioannis P. Trougakos, Meletios A Dimopoulos, Evangelos Terpos, Ioanna Andreadou
Panagiotis Efentakis, Angelina Choustoulaki, Ioannis V. Kostopoulos, Aimilia Varela, Anastasios D. Georgoulis, George Tsekenis, Charikleia Gakiopoulou, Ioannis Ntanasis‐Stathopoulos, Constantinos H. Davos, O.E. Tsitsiloni, Meletios A Dimopoulos, Evangelos Terpos, Maria Gavriatopoulou, Ioanna Andreadou
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