Elevated de novo lipogenesis, slow liver triglyceride turnover, and clinical correlations in nonalcoholic steatohepatitis patients

Eric Lawitz; Kelvin W. Li; Edna Nyangau; Tyler Field; Jen‐Chieh Chuang; Andrew N. Billin; Lulu Wang; Ya Wang; Ryan S. Huss; Chuhan Chung; G. Mani Subramanian; Robert P. Myers; Marc Hellerstein

doi:10.1016/j.jlr.2022.100250

Related publications

Article2019

Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease

Gordon I. Smith, Mahalakshmi Shankaran, Mihoko Yoshino, George G. Schweitzer, Maria Chondronikola, Joseph W. Beals, Adewole L. Okunade, Bruce W. Patterson, Edna Nyangau, Tyler Field, Claude B. Sirlin, Saswata Talukdar, Marc Hellerstein, Samuel Klein

Article2018

Acetyl-CoA Carboxylase Inhibitor GS-0976 for 12 Weeks Reduces Hepatic De Novo Lipogenesis and Steatosis in Patients With Nonalcoholic Steatohepatitis

Eric Lawitz, Angie Coste, Fred Poordad, Naim Alkhouri, Nicole Loo, B. Mccolgan, Jacqueline M. Tarrant, Tuan Nguyen, Ling Han, Chuhan Chung, Adrian S. Ray, John G. McHutchison, G. Mani Subramanian, Robert P. Myers, Michael S. Middleton, Claude B. Sirlin, Rohit Loomba, Edna Nyangau, Mark Fitch, Kelvin W. Li, Marc Hellerstein

Article2004

Adipose tissue triglyceride turnover, de novo lipogenesis, and cell proliferation in humans measured with<sup>2</sup>H<sub>2</sub>O

Alison Strawford, F. Antelo, Mads Christiansen, Marc Hellerstein

Article2020

Energy Restriction Decreases Triglyceride Turnover in Subcutaneous and Visceral Adipose Tissue, but Has No Effect on Hepatic De Novo Lipogenesis in Obese Zucker Rats

M. Alan Dawson, Stephen R. Hennigar, James P. McClung, Mahalakshmi Shankaran, Edna Nyangau, William J. Evans, Marc Hellerstein, Tyler Field, Alyssa M. Kelley, Bradley J. Anderson, Stefan M. Pasiakos, Claire E. Berryman

Article1996

Regulation of Hepatic De Novo Lipogenesis in Humans

Marc Hellerstein, Jean‐Marc Schwarz, Richard A. Neese