Effects of the Oral Direct Renin Inhibitor Aliskiren in Patients With Symptomatic Heart Failure

John J.V. McMurray; Bertram Pitt; Roberto Latini; Aldo Maggioni; Scott D. Solomon; Deborah Keefe; Jessica Ford; Anil Verma; Jim Lewsey

doi:10.1161/circheartfailure.107.740704

Abstract

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Addition of aliskiren to an ACE inhibitor (or angiotensin receptor blocker) and beta-blocker had favorable neurohumoral effects in heart failure and appeared to be well tolerated.

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